By Roxanne Cruz


Before, thousands of residents die because certain medicine or vaccination was not yet available in the market. However, due to the discoveries of these geniuses, curing the once deadly diseases are now possible. Since medical science plays a very fascinating role in medicine science, clodronate liposome was discovered, accidentally. Because of the great role it plays in curing and treating diseases, it will surely be of great importance to medical science.

Clodronate also known as clodronate disodium and clodronic acid is a first generation non nitrogenous bisphosphonate. It is a drug scientifically approved, tested, and used to prevent and treat the cases of osteoporosis especially to the women who have reached the post menopausal period. It is also used in the experimental medicine to deplete macrophages.

Macrophages are white blood cells found inside the tissue. They produced through the division of white blood cells that was formed in the spleen and bone marrow or monocytes. They eat foreign and cell particles after its formation. Macrophage is said to be the core of the immune system.

Liposomes, in cell biology, are the microscopic sac that are composed of fatty liquids. They are used in the experimental research of the cell. It can be supplied with drugs used in curing cancer and other diseases. It usually contained of liquid solutions and composed of phospholipids.

Medical science discovered clodronate liposome that will function in the suppression of macrophages. It is known to be the fighter against microorganism. Aside from defending the body from the organisms that will infect and impair the system, it can also be the source of the disease.

In most circumstances, the immune system helps the body cope up diseases like fever and colds. However, when it is damaged, it will attack all the cells including the healthy ones. With a stroke of misfortune, several grave disorders will take place.

The system protects the body from foreign invasion, as mentioned earlier. However, it will also create damages resulted by transplant rejection. This rejection happens when a a newly transplanted organ was placed in the body. As this happens, the system will attack the cells forcefully leading to rejection. One of the effects of the rejection is the autoimmune disorder or the identification of healthy cells wrongly and trying to fight off them because they thought that they are foreign.

Because of these cases that will damage the body defense against harmful organisms, doctors and scientists fumbled upon the discovery of liposome. This medicine is made of bisphosphonate that will help lessen the quantity of macrophage. As soon as macrophage detects that this drug transported inside the body is foreign, it will automatically engulf it whole through phagocytosis.

Clodronate liposome is said to treat cancer through the increase absorption of plasma. It also improves the effects of anti tumor drugs to treat cancer. Even if this discovery is really fascinating, consult the medical doctor first before deciding to take this drug. This is for your safety, after all.




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